Caffeine and Metabolites

Caffeine is a psychoactive stimulant of the central nervous system that is extensively consumed worldwide.  MS-based research into the kinetics/metabolism of this compound and its metabolites (e.g., paraxanthine, theobromine, theophylline) has revealed insight into its health impact and abuse in humans.  Studies further suggest an influence on pharmacological activity and neurodegeneration (e.g., Parkinson’s disease); thus, strengthening a need for its robust analyses.  CIL offers stable isotope-labeled caffeine and a collection of isotopically labeled metabolites (e.g., methylxanthine, theobromine, paraxanthine) for basic and translational quantitative research.  These research grade materials are available in various labeling patterns and in their neat form.

For additional information, please see our Stable Isotope Standards for Mass Spectrometry catalog.