Methionine Cycle

The essential amino acid L-methionine (Met) is an important contributor to several metabolic pathways and plays a key role in many metabolic functions (e.g., epigenetics, detoxification, lipid membrane homeostasis).  The Met cycle is closely linked to the folate metabolic pathway and is therefore indirectly tied to the physiological functions modulated by the folate cycle.  Imbalance or abnormal functioning of the Met cycle has been reported to cause cancer, diabetes, and other systemic diseases.  To help with biomarker assessment and the study into disease-related mechanisms, CIL offers a number of stable isotope-labeled Met cycle compounds (e.g., S-adenosyl-L-homocysteine or SAH, homocysteine, methionine).  These materials are research-grade and available in their neat form.

For additional information, please see our Stable Isotope Standards for Mass Spectrometry catalog.