Folate Cycle

The folate metabolic pathway plays a central role in many physiological processes (e.g., redox and amino acid homeostasis) and biochemical reactions.  The reactions include, but are not limited to, the synthesis of nucleotides and amino acids (e.g., methionine, homocysteine) and mitochondrial protein translation.  Inhibited or abnormal functions have been linked to systemic diseases (e.g., cardiovascular, neurodegenerative).  To assist in compound identification/quantification and their functional assessment, CIL offers a collection of folate cycle-related metabolites.  Included in the offering is the metabolite 5-methyl-tetrahydrofolate (5-methyl-THF), which is linked to the methionine cycle, as well as other metabolic intermediates and reactants.  These are available as research grade materials in predominantly their neat form.

For additional information, please see our Stable Isotope Standards for Mass Spectrometry catalog.